LIOFeron® TB/LTBI - Tuberculosis IGRA (IVD)

LIOFeron® TB/LTBI is an interferon-gamma release assay (IGRA) for detection of active TB and latent tuberculosis infection (LTBI). It is based on Lionex proprietary blood collection tubes and Lionex ELISA components. Our standalone software supports full data analysis of LIOFeron® TB/LTBI ELISA results.

View product page →
View analysis software →

Assay Principle

LIOFeron® TB/LTBI IGRA assay principle - whole-blood stimulation and interferon-gamma ELISA detection

LIOFeron® TB/LTBI Kit

Contains both components of the Lionex interferon-gamma release assay, including our proprietary blood stimulation tubes and interferon-gamma ELISA reagents. Optimized for professional laboratory workflows in active TB and LTBI detection. View product page →

Resources

For instructions for use, MSDS, declarations of conformity, and analysis software, see: LIOFeron® documentation →
LIOFeron® analysis software →
LIOFeron® FAQ →

Citations

  1. Della Bella C, Spinicci M, Alnwaisri HFM, et al. LIOFeron® TB/LTBI: A novel and reliable test for LTBI and tuberculosis. Int J Infect Dis. 2020;91(2):177-181. PMID: 31877486 Full text (PDF)
  2. Gong W, Wu X. Differential Diagnosis of Latent Tuberculosis Infection and Active Tuberculosis: A Key to a Successful Tuberculosis Control Strategy. Front Microbiol. 2021;12:745592. PMID: 34745048 Full text (PDF)
  3. Bayaa R. Development and clinical evaluation of new blood-based tests for improving the diagnosis of pulmonary tuberculosis and identification of candidate biomarkers for treatment monitoring: a multicenter study in moderate and high incidence settings [doctoral thesis]. Lyon: Université de Lyon; 2022. HAL record Full text (PDF)
  4. Della Bella C, Motisi MA, Venturini E, et al. Performance evaluation of the LIOFeron® TB/LTBI IGRA for screening of paediatric LTBI and tuberculosis. Eur J Pediatr. 2025;184(2):147. PMID: 39831989 Full text (PDF)