Select Page




The TB Rapid test of LIONEX has shown excellent results in a study published in the International Journal TUBERCULOSIS


LIODetect TBST® publication in International Journal with excellent results 



LIONEX has introduced a new IGRA test for Tuberculosis and Latent Tuberculosis Infection (LTBI called  LIONEX®TB/LTBI


LIOFERON publications in peer-reviwed International Journals with excellent results 


The complete EndoTrap® product range as well as EndoGrade® Ovalbumin have been discontinued by Hyglos as of 31 December 2017, instead LIONEX GmbH, Braunschweig, Germany, is now the manufacturer and exclusive supplier of these products.

EndoTrap® family: Endotoxin removal products are now available from LIONEX, Braunschweig, GERMANY

LIOSpot®TB human

LIONEX has developed a new ELISPOT test which, for the first time, can differentiate between LTBI and active TB. LIOSpot® TB human is protected by international patents of LIONEX.

…read more/Video




LIONEX Tuberculosis antigens, Mycobacterial antigens


LIONEX has greatly expanded the number of recombinant  and native antigens of Mycobacterium tuberculosis.which are now available to the scientific community. All products of LIONEX are exclusively produced by LIONEX in Germany.

Well known antigens are: ESAT6, CFP10, Ag85B, 16kD (Alpha Crystalline, HSP), ALADH, HSP70, HSP65, HSP60, MPT64, MPT70, MPT85, LAM, LAM+LM+PIM, PIM, 19 kDaantigen (Rv3763), PstS1antigen (Rv0934), PstS3antigen (Rv0928), Antigen 85ARv3804c, Antigen MPT51 (Rv3803c), NarL (Rv0844c), Apa (Rv1860), SigC (Rv2069), SigJ (Rv3328c), GlnA1 (Rv2220), HSP20 (Rv0251c), LppO (Rv2290), Tpx (Rv1932), Rv2626c Hrp1, Ppe57 (Rv3425), Ppe58 (Rv3426), Ppe65 (Rv3621c), TB16.3 (Rv2185c), PE35 (Rv3872), BcpB (Rv1608c), HBHA (Rv0475), ICL (Rv0467), CFP7 / TB10.4 (Rv0288), esxS (Rv3020c), whiB1 (Rv3219), KatG (Rv1908), PPE39 (Rv2353c), PPE68 (Rv3873), PPE42 (Rv2608), PPE38 (Rv2352c), DEVR, DOSR (Rv3133c), acg (Rv2032).

Many more are listed in the Catalogue .


is the best affinity product for endotoxin removal from bacteriophage preprations

Read the publication from Finnland on EndoTrap HD, 2019

Exclusive manufacturer & supplier of endotrap® 
Lioferon®: A new igra test for latent tuberculosis infection (LTBI)/TB

World’s Leading Producer And Source Of Mycobacterial Antigens For Diagnostics And Vaccine Development for tuberculosis

Lionex Gmbh

World's Leading Producer And Source Of TUBERCULOSIS/ Mycobacterial Antigens For Diagnostics And Vaccine Development

LIONEX  is a German biotech company active in the fields of biomedicine and human health with special emphasis on TUBERCULOSIS (TB). Our focus is on research and In-Vitro-Diagnostic (IVD) product development for infectious diseases and cancer. LIONEX has recently launched a new IGRA (Interferon Gamma Release Assay) diagnostic test  called LIOFeron®TB/LTBI for LTBI (Latent Tuberculosis Infection). It may also react positive in TB patients also but, as for other similar IGRA tests on the market, it cannot differentiate between LTBI and active TB.


LIONEX is a leading manufacturer of highly purified, endotoxin free, mycobacterial antigens for research on tuberculosis and other mycobacterial diseases.

LIONEX is the licensed, exclusive manufacturer and distributor of a widely known family of endotoxin removal resin under the brand name EndoTrap®. EndoGrade®Ovalbumin is another useful product for research on vaccine development.

Bovine tuberculosis tests are also available for research.

LIONEX has state of the manufacturing facilities for IVD-Lateral Flow Tests. All products are manufactured in Germany. All productions are done under  ISO compliant conditions.

We are a highly reliable partner for OEM products for companies active in manufacturing and distribution of such products worldwide.

LIONEX partners and clients are large diagnostic companies, distributors, research institutions, universities, hospitals located on all continents.



If you have any question please contact us


© 2018 Lionex GmbH

Last update:  Mar 31, 2023 @ 12:35 Lionex GmbH

TÜV Rheinland